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Liquid Syrup Manufacturing Process –
Application & Process :
THE BOMBAY ENGINEERING WORKS has been designed & manufacturing preparation vessels and has consolidated a process knowledge concerning sterile injectable solution, dispersions, ophthalmic products, syrup and suppositories.

Preparation Vessels & Tank :
• Extremely hygienic processing.
• Least manual handling.
• Design compliance with cGMP
• Capacity up to 5,000 Liter.
• Product Contact AISI 316L
• Atmospheric, Vacuum or Pressure Operation.
• Jacket for heating & cooling.
• Vessel Inside Pressure (-1 /+3 Bar)
• Heating Jacket Pressure (-1 /+6 bar)
• Heating by steam or hot water circulation.
• Thermal Insulated.
• Mechanicals or Electro polishing of internal surface.
• Welded, flanged or hinged type cover
• Integrated Cleaning in Place-CIP.
• Sterilizing In Place-SIP as an Option.
• Portable execution on request.
• Validation protocols & Instrumentation celebration.

Variable Speed Agitation :
• Agitator can be top or bottom driven or magnetically driven.
• Propeller type, Anchor type provided with High speed disperser or rotor-stator homogenizer.
• Single or double mechanical seal.

Fully automatic Liquid Syrup Manufacturing Plant consisting of :
• Sugar Charging / Transfer System.
• Sugar Melting Vessel with mixing stirrer.
• Basket Filter & Transfer Pump.
• Syrup Manufacturing Vessel with stirrer.
• Inline Homogenizer.
• Zero Hold up Filter press.
• Storage Tank with stirrer.
• Interconnecting pipeline.
• Transfer Pumps.
• Integrated automatic control panel.
• Working Platform.

UNIQUE FEATURES OF THE FACILITY :

  • The liquid oral manufacturing plant is designed to be operated by one operator and one helper, saving on precious manpower costs.
  • Sugar syrup and manufacturing vessels are provided with limpet coils for
    heating and cooling, designed for internal vacuum to facilitate transfer of sugar directly from stores to sugar syrup vessel.
  • Sugar syrup is transferred to manufacturing vessel through online sugar syrup pre-filter by vacuum.
  • Entry of all propeller agitators are from bottom through a specially designed cartridge mechanical seal with TC/TC seal face.
  • The advantage of the bottom propeller agitator over the conventional agitator is that there are no vibrations of shaft, no couplings in the drive assembly, leading to lower maintenance cost for liquid oral manufacturing plant.
  • Pipes, pipe fittings and valves are of SS 316, seamless, internally electropolished with DIN standard unions and silicon Gaskets.
  • Manhole of all the vessels are equipped with davit fitting and the cover of the manhole slides instead of being lifted.
  • Automation available, appropriate for the intended process function,
    including CIP and SIP :
    • Controls of all function by PLC Controls with HMI Touch screen.
    • Level controls by means of capacitance probe or electronic load cells.
    • Digital indication and controls of all process parameters for Process time, agitator speed, temperature, pressure & level.
  • CAPACITIES AVAILABLE : : 50 Ltrs. to 20,000 Ltrs.
Capacity 1000 Ltrs 2000 Ltrs
Sugar Syrup Vessel –
Gross Capacity 1250 2400
Working Capacity 1000 2000
Agitation Motor 7.5HP/3 Phase 415 VAC/50Hz / 1400 rpm 7.5HP/3 Phase 415 VAC/50Hz / 1400 rpm
Sugar Melting Vessel –
Gross Capacity 850 1500
Working Capacity 600 1200
Agitation Motor 5HP/3 Phase/415 VAC 50Hz.1440 rpm 7.5HP/3 Phase 415 VAC/50Hz / 1440 rpm
Storage Vessel –
Gross Capacity 1250 2400
Working Capacity 1000 2000
Agitation Motor 5HP/3 Phase/415 VAC 50Hz.1440 rpm 7.5HP/3 Phase 415 VAC/50Hz / 1440 rpm
In line Mixer cum Micronizer SS316/5HP/2800 rpm SS316/7.5 HP /2800 rpm

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