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Talcum Powder manufacturing Plant :
www.cosmeticmachinery.com/talcum-powder-manufacturing-plant/

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Ointment Manufacturing Plant -
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The Bombay Engineering Works
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Tray Dryer :

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RAPID MIXER GRANULATOR :

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FLUID BED TIPPER :
www.bombayengg.com/fluid-bed-tipper/

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"THE BOMBAY ENGINEERING WORKS "

Established in the year 1964, The Bombay Engineering Works have carved a niche as a prime manufacturer, supplier and exporter of Pharmaceutical, Chemical, Food, Cosmetic, Ayurvedic and Herbal Machineries.

We have been dealing in wide range of Pharmaceutical, Chemical, Food, Cosmetic, Ayurvedic and Herbal Machineries that is an ideal amalgamation of utility and quality. We work towards the vision of persevering to incorporate modern innovations set by prevalent international standards in every The Bombay Engineering Works product according to customer requirements.

We have adopted stringent quality measures that are practiced from the initial stage of production and continue till the final packaging of our products. We give prime importance to trust transparency and maintenance of cordial relations with our clients and thus have been able to maintain a satisfied list of customers.

We have a well-equipped infrastructural base equipped with advanced and latest technology machinery and equipment. All the machines and tools are managed by a team of experienced and skilled experts, which works in close coordination with each other for offering what a client looks for. Starting from the procurement of raw materials to the delivery of end products, all the production stages are inspected by experts. With huge warehousing facility and fully fledged packaging unit, we have been meeting bulk demands of the clients on time.

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“Rapid Mix Granulator (Operation and Cleaning Guide) : The Bombay Engineering Works”

Operating principle :
A rapid mix granulator is a multi-purpose mixer/processor equally suitable for high speed dispersion of dry powders (including effervescent powders) and their granulation with aqueous or organic solvents.

The equipment is designed to achieve rapid mixing and the formation of consistent granules required for the production of high quality pharmaceutical tablets for solid dosage forms of medication. Good mixing and control of granule size leads to fast tableting speeds and high quality products with low rejection rate.

A rapid mixer granulator usually comprises mixing bowl with a bottom entry agitator or impeller for mixing the materials and a side mounted chopper for granulating the mixture. The operating principle is based on agitation of the contents of the bowl at moderate speed and then running the blade of the chopper at high speeds to achieve granulation.

Broadly the operating process therefore takes place in 3 steps -
• Dry materials are mixed at high speed for typically 3 to 5 minutes.
• The mixer is set at a slow speed and liquid binder is added to the dry materials. Mixing of the wet materials typically takes a further 5-10 minutes. The impeller breaks up the mass of material into smaller fragments or granules.
• Wet granulation is achieved by running the mixer at high speed and it typically takes another 5 to 10 minutes to produce granules of 0.5 to 1.5 mm average diameter. The actual granulation time depends on the nature of the starting materials (e.g., density and particle size), the binder, and the speed of the chopper. In this step it is the design and speed of the chopper that determines the uniformity and size of the produced granules. The chopper runs at high speed usually above 200 rpm, and typically between 1200 and 2000 rpm.

Operating procedure :
A. Pre-start Up -
• Ensure that the processing area is clean.
• Check that the correct materials have been selected for the granulation process.
• Remove the “cleaned” label from the granulator after checking the information provided (especially previously used materials).
• Place the equipment label on the machine.

B. Start Up and operation -
• Use protective latex gloves when loading and unloading materials.
• Open the lid of the granulator and load the material to the bowl as per the sequence indicated in the Batch Manufacturing Record (BMR) or specification.
• Close the lid and secure the two locking clamps.
• Fix the dry mixing speed as specified in the BMR. Turn on the power and start the dry mixing process. Run for the specified mixing period.
• Slow the mixer impeller as specified in the BMR to the speed required for binder addition.
• Add the binder solution by supplying through the solution inlet port.
• Check the impeller speed is as per BMR and for the wet mixing process, and run for the required period.
• Increase the speed and set the chopper speed to that required for granulation. Check regularly to ensure that granulation is complete.
• Open the discharge gate and allow the wet mass to flow into a clean FBD bowl, located under the discharge port.

C. Shut Down -
• Stop the chopper and impeller, and open the equipment top lid. Remove any remaining mix by scraping it from the sides of the bowl.
• Check that all materials are removed.
• Switch off the main power supply.

Cleaning Procedures -
1. Cleaning during batch changeover, but with the same product -
• Check that the equipment and area around the equipment is clean.
• Remove the “cleaned” label from the machine.
• Place the equipment “in use” label on the machine.

2. Cleaning during product changeover -
• Check that the equipment and area around the equipment is clean and free from waste or materials from previous products.
• Check and review the “rinse water analysis report” and attach to the BMR.
• Remove the “cleaned” label from the machine.
• Check the relative humidity and room temperature, making sure to document it in the BMR log.
• If the temperature is not within the specified limit, inform the maintenance personnel and do not proceed until the temperature and relative humidity is changed to the required norm.

3. Cleaning at shutdown (e.g., end of day cleaning), or during batch changeover of same product (of ascending potency) -
• Use a vacuum cleaner or lint free cloth to remove loosely stuck powder.
• Dismantle the machine parts and remove them in sequence:
1) Agitator dome
2) Chopper blade
3) Stainless steel bolt
• Use a lint free cloth or vacuum cleaner to clean the dismantled parts.
• Clean the machine and disassemble the parts with lint free cloth.
• Clean the processing area as per the SOP.
• Assemble the parts once cleaned.
• Affix “cleaned” label to equipment.
• Document the cleaning details in the BMR log.

4. Cleaning at Product Changeover (same product of descending potency) – Preventative Maintenance of

Contact Parts -
• Clean the mixer and the assembly surface using a moist duster followed by a dry clean duster.
• Fill the bowl with 1/3 of its capacity with water, close the lid and run the mixer and chopper for 5 minutes.
• Collect the washing water e.g., by placing stainless steel drum under the discharge port.
• Open the top lid, remove the agitator blade, and dome by loosening the locking nuts.
• Dismantle the chopper blade by loosening the belt and then remove the blade and washer.
• Transfer the agitator blade and chopper to the washing area, clean both items under a jet of water, and scrub using a clean nylon brush.
• Scrub sticky powder with nylon brush and wash the bowl thoroughly to remove any visible sign of material. .
• Check the underside of the chopper blade, dome and chopper crevices, discharge ports and locking nuts to make sure that the equipment is visibly clean.
• Rinse the machine and the parts with purified water. Send a sample of the rinse water to QA to confirm that it is free from materials from the previous batch.
• Place the “cleaned” label on the machine.
• Document the cleaning details in the BMR log.

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Filling Technologies Used in Pharmaceutical Industries in Various Countries -

Most pharmaceutical products are packaged as either liquid or powders. Both of these products require advanced machines to handle their manufacturing and packaging.
Liquid filling machines

There are a number of technologies that are used in different nations for filling liquid medicine. They range from small machines to more complicated systems.

Table top filling machines
These were early machines used in packaging drugs and food. They ranged from manual, semi automatic and fully automatic systems. They use a pump to deliver the liquid to bottles. They are still in use in the developing nations, Africa, China and India. They are used by herbal medicine companies or those operating at a small scale. They use electric pumps, peristaltic movement and pneumatic systems. Containers are handled by hand and this increases their susceptibility to biological and chemical contaminants.

Advanced liquid filling machines for vials and ampoules
Liquid filling machines are utilized by many pharmaceutical companies in the world. They pass most drug agency regulation and codes since they achieve aseptic filling. These can be classified in terms of container type, speed, features, number of fill per operation and functionality.
The mechanism helps machine to fill vials or ampoules, an advanced method of cleaning, disinfecting, sealing and capping the containers.

Though different liquid filler employ a several filling techniques, the basic mechanism entails the use of piston, syringes and nozzles. The movement of piston sucks a metered quantity of the drug which is then delivered to the ampoules.

These machines are very popular in India, China, USA and Europe and are used by a vast number of pharmaceutical companies in packaging. Advanced sensors are used to monitor volume, container, speed, movement, sealing and other processes.

Liquid bottle / Monoblock filling machines
These are advanced modern machines used to pack liquid chemicals into bottles. They are widely used in pharmaceuticals drug packaging for local and export market. They have advanced features for handling bottles, cleaning them, metering the fluid depending of density, viscosity and chemical properties, pouring the right quantity and filling.

The monoblock type is widely used as it is a complete set will advanced measuring and filling system, ROPP (roll-on-pilfer-proof) where a filled bottle is sealed with a screw able bottle cap inserted by rotating capping machines that descends on the bottle, screws the cap and also forms a tamper proof tuck broken during use.

Dry powder filling machines :
Dry powder filling machines are used as alternative to liquid methods. They are widely applied in packing powders that will be remixed in hospitals or by patients. The main machines applied include

Vacuum/ Injectable dry powders :
This is an advanced method of packing dry powder. The sterile powder is stored in a hopper that uses agitation to move and mix the material. Then powder wheel uses a vacuum to suck the required amount of materials from the hopper. A doctor wheel scoops excess material before it is delivered to the bottle. They have advanced features are widely used in economical packing in North America, China, India and Europe.

Auger type filling machines :
The auger type is more precise and has unbeatable accuracy in filling powders. It features a rotating auger that sucks a definitive amount of powder and transports it to bottles. This is followed by sealing and labeling.

Advanced specialized filling machine :
In addition, many export machines are customized to suit the user needs in terms of bottle size, capping and sealing method as well as other features.

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“Contra Rotating Mixers : THE BOMBAY ENGINEERING WORKS”

Contra rotating mixers are typically used when thick emulsions are produced by a bottom entry emulsifier or homogenizer. They are also very useful for multi task vessels where different process duties are required.

Advantages :
Contra rotating mixers have the advantage of utilizing the benefits of a turbine unit with the benefits of an anchor / scraper. Contra rotating mixers offer excellent mixing throughout the vessel as viscosities increase due to their double mix system.

A contra rotating mixer is fitted with two drives; an anchor / scraper drive and a centrally mounted turbine drive. In effect it is two mixers joined together. The wet end can be complete and installed into the tank prior to the vessel being completed or can be fully split to allow simple installation / removal.

Areas of Applications :
The mixer is highly versatile and mostly used for manufacturing Tooth Paste, Creams, Cosmetics and other viscous products.

Operation Principles :
Contra Mixer as the name suggests works on the principle of Contra rotation of Blades for simultaneous beating and scraping operation. The Mixing Assembly consists of series of paddle type blades of appropriate shape to move the material back towards the centre of the container.

The paddle type blades are provided on the central shaft which runs through a hollow shaft on which other sets of blades are welded. Both the sets of blades intermeshes with each other and rotates in clockwise and anti-clockwise direction respectively and one sets also scraps the container wall for thorough and uniform mixing of the material.

The mixer is so designed to withstand high vacuum applied during the process for optimum mixing. Contra Mixer is provided with a jacket for cooling or heating as per the application. The vessel shall have a shell of suitable thickness with a hemispherical bottom and flanged top dish made out of SS 316 plate.

The vessel shall be jacketed with MS jacket (SS 304 jacket provided on extra cost on demand, if required) of suitable with stiffeners suitable for steam pressure of 4 to 5 Kg/cm2. The jacket shall be insulated with 50 mm thick glass wool insulation and shall be cladded with 16 SWG M.S. or SS 304 materials. The vessel shall be suitable for 600 to 700 mm of Hg vacuum and internal pressure of 3 Kgs / cm2.

Salient Features :
• All contact parts AISI 304 or 316,304L or 316L.
• Jacketed mixers are provided for heating of products during mixing.
• Provision to mix / blend the viscous products under vacuum for de-aeration purpose.
• High shearing action because of contra rotary motion & homogenizer.
• Mechanical seal is provided instead of stuffing box for main shaft sealing for vacuum operation.
• Anchor blade assembly with adjustable Teflon scrappers is provided to avoid localized heating & ensure uniform mixing.
• Top drive & agitator assembly can be lifted & lowered by motorized as well as hydraulic operations if required.
• Smaller version of Contra Rotary Mixers is provided with lifting arrangement for the bowl instead of top drive & agitator assembly.
• Pneumatic system is also available for lifting & lowering top drive & agitator assembly for smaller version of Contra Mixer.
• Available in Standard Model and GMP Models.

• Capacity Available : 50 to 10,000 Ltrs.

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“Ointment Manufacturing Plant : The Bombay Engineering Works”

Ointment Manufacturing Plant is an ideal tool for the pharmaceutical & cosmetic industries for the production of Ointment, Cream, Lotions, Tooth Paste & other emulsions & homogenizations.

It is specially designed to take care of two critical factors which directly affect the quality of the Ointment/Creams.
• Minimum man handling of Ointment.
• Negligible vacuum drop during mixing & blending.
• Needless to say, it also provides the benefits of the effective manpower utilization.

Features of Ointment Manufacturing Plant :
• Easily cleanable and completely untouched process, less chance of contamination.
• All contact parts made of Stainless Steel 316 and non- hence contact part ss 304 material.
• All pipelines are electro polished from inside and joints are easy openable.
• Complete cover lifting arrangement to facilitate cleaning at the time of product change over.
• Especially semi-contra & Double contra designed anchor stirrer with flexible Teflon scrapers.
• The plant is provided with pre-mixing wax and water phase vessels and the main manufacturing vessel.
• The main vessel is provided with a slow speed anchor agitator for mixing and a bottom high speed homogenizer for emulsifying.
• Variable speed drive provided for main anchor stirrer assembly for different speeds.
• Jacketed vessels for heating/cooling processes.
• Inspection glass with illumination.
• Specially designed inline filters can also be provided to ensure proper filtration.

Optional Requirement are :
1) Load cell for accurate weighing.
2) PLC based control panel for process automation.
3) Contra type agitator for calcium base toothpaste.
• The Ointment Manufacturing Plant / Cream Manufacturing Machine is suitable for manufacturing pharmaceutical ointments, sterile preparations, cosmetic creams, suspensions, gels, etc.

Equipments of Ointment Manufacturing Plant :
• Wax heating Vessel.
• Water Melting Vessel.
• Manufacturing vessel.
• Storage vessel.
• Interconnecting pipeline.
• Pumps -Lobe Pump and metering pumps.
• Integrated automatic control panel.
• Working Platform.

Process Description of Ointment Manufacturing Plant :
• All vessels are manufactured from S.S. 316 grade stainless steel sheets and are cGMP compliant construction.
• The vessels are Jacketed, insulated, cladded and with suitable agitator assembly in each vessel.
• Wax is melted in Wax melting vessel; Water is heated in water heating vessel.
• Both wax and water are transferred into the manufacturing vessel automatically through vacuum.
• In manufacturing vessel both wax and water are homogenized to make a uniform emulsion and cooled by passing chilled water into the jacket of manufacturing vessel.
• After the emulsion is formed active ingredients/colors etc. are added and are thoroughly mixed and homogenized.
• The same is transferred by bump pump into the storage vessel. From the storage vessel it is automatically transferred into the filling machine by means of metering pump.
• Flow rate of metering pump can be set as per your tube filling machines speed and capacity.

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Are you looking for a professional company specialising in the production of machines and equipment for the cosmetics industry, with bottling and packaging plants for your cosmetic products?

The Bombay Engineering Works is an Indian company specialising in the design and construction of machines for small, medium and large-sized business that operate in the chemical, pharmaceutical, cosmetics, food industries etc..
The Bombay Engineering Works is able to boast a very wide customer base of Indian and international clients due to a long history operating in many merchandise sectors.

The cosmetics industry is constantly evolving and changing, in order to offer its many customers products that are always new and original. This applies both to the raw materials used, that are increasingly safe, and the product's look that must be innovative, competitive and striking.

The Bombay Engineering Works supplies plants, machines and equipment for the cosmetics industry. The company has the capacity to design, develop and construct in-house automatic and semi-automatic machines, both in-line and rotary, for bottling, dosing and packaging operations.
Types of machines supplied include fillers, dosers and dispensers, cappers, crimpers, sealers, labellers, as well as machines for filtering, mixing and storage, such as filter presses, mixing tanks and storage tanks, agitators and turbo-emulsifiers.

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We “THE BOMBAY ENGINEERING WORKS”, are the noteworthy Manufacturer & Exporter of finest quality range of Industrial Filling Machine, Labeling Machine, Bottle Washing Machine, Sealing Machine, Turntable Machine, Online Visual Bottle Inspection Machine, etc. Our offered products are widely used pharmaceutical companies for different purposes. In order to bring fluency in our production rate, we have setup state-of-the-art infrastructure base armed with sophisticated machinery and technologies.

The products offered by us are manufactured by our skilled professionals using high grade factor inputs and innovative technology in order to ensure unmatched quality. Manufactured in compliance with the predefined quality standards, we also make available these machines in various specifications as per the specific demands of our clients.

The well-developed infrastructure of our company has contributed towards the enormous growth and success of our firm. Divided into several departments such as procurement, production, quality control and warehousing & packaging, our infrastructure is well connected with the major means of transportation for timely delivery of the products.

The professionals associated with us work in a cohesive manner to accomplish the predetermined goals of the firm. Being a client-centric firm, we have a prime objective to attain the maximum satisfaction of our prestigious clients. Our immense industry experience helps us in catering all specific demands of our clients.
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“ZERO HOLD UP SPARKLER FILTER PRESS MANUFACTURERS IN INDIA – THE BOMBAY ENGINEERING WORKS”

We are leading at Zero Hold Up Sparkler Filter Press manufacturers in India. With experience and knowledge, we have built broad client base across worldwide. This Zero Hold Up Sparkler Filter Press machine is manufactured by us with very high quality material and as per the international industry standards to meet the changing needs.

Zero Hold Up Sparkler Filter Press manufacturers in India has been tested at various levels and it requires very low maintenance. The Zero Hold Up Sparkler Filter Press manufacturers in India consists of an assembly of filter plates and filter cloth with perforated S.S. supporting screens enclosed in an S.S. shell. The assembly is equipped with a pump to pressurize the liquid through the stack of horizontally arranged filter plates. With the help of our professionals, we are able to put forth widely appreciated zero hold sparkler filter press at pocket friendly prices.

Owing to our expertise in this domain, we are involved in offering a broad range of Zero Hold up Filter Press to our clients spanning Worldwide.

APPLICATION :
To filter final product in Pharmaceuticals, Perfumes, I. V. Fluids, Dyes & Chemicals, Activated carbon, Pesticides, Cosmetics, Varnishes, Polymers, Resins & Paints, Sugar syrup, Food, Plant Water Polishing, Fruit juice, Soft drink, Beer & Liquors, Edible & Non Edible oils.

SIZE AVAILABLE :
8” / 14” / 18” / 24” & 33” dia.

OPERATION :
• The liquid to be filtered is forced in the chamber by the Transfer pump, where it finds its way to the top of the filter media of each plate through circular opening on the side of the plates.
• Under pressure clear Liquid passes through the filter media leaving suspended particles on top of the filter.
• The clear filtrate runs down through central channel formed by the interlocking cups and exists through the outlet valve.

FEATURES :
• Single pass clear filtration.
• Full batch recovery of the filtrate.
• Easy install inside cartridge assembly.
• Complete cake retains on the plate.
• Uniform distribution of cake on each plate.
• Reduce the cost of treatment of catalyst, Toxic Chemicals.
• Less exposure to the operating person.
• No contamination of the internal surface of the shell.

ADVANTAGES :
• Zero retention in filter vessel.

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Fluid Bed Dryer Uses and Applications -

Fluid bed dryers :
The average consumer has most likely never even heard of them. But in the world of bulk processing, fluid bed dryers have established themselves as dependable and multi-functional processors; capable of completing a variety of critical tasks.

Fluid Bed Dryers :
Fluid bed dryers, as their name suggests, are used for drying materials such as granules, tablets, powders, fertilizers, and plastics. They are particularly popular in production industries like:
• Chemical
• Pharmaceutical
• Food
• Dairy
• Metallurgical
• Dyes
• Other process industries

Fluid bed dryers work on the principle of fluidization, a process in which hot gas or air is introduced into the spaces between solid particles. Upward forces on the particles increase as the air’s velocity increases causing them to equal the gravitational forces below.
A state of fluidization now exists as the particles are suspended in what appears to be a boiling bed of liquid. Each particle is in direct contact with, and surrounded by, the hot gas or air – creating an efficient and uniform drying process.

Fluid Bed Granulation to the Rescue :
Powders do not work well in many applications. They are loosely packed, lack uniformity, and do not flow well. So they need to be crystallized into granules. In pharmaceutical manufacturing, for instance, granulation means aggregating various primary powder materials to form larger granules. These granules will have greater density, better followability, and uniformity.
Granulation systems can be combined with fluid bed dryers so that the drying, mixing, granulation, finishing, and cooling operations are completed in the same process.

The Importance of Dryers to the Pharmaceutical Industry :
While it’s true that fluidized bed drying can be used in a variety of industries, arguably it has its greatest impact on pharmaceuticals. Fluid bed drying technology has replaced the traditional method of drying products in trays; the result of which has been considerably shorter drying times along with uniform drying conditions.

Fluid bed dryers provide the best solution for drying many products, but especially products within the pharmaceutical industry. With the system, inlet air temperature can be controlled so that the correct amount of moisture evaporates from the surface of the granule. An inlet air temperature that’s too high can result in a surface crust that prevents deeper moisture from being transported to the surface, delaying the drying process rather than accelerating it.

What You Need in a Fluid Bed Dryer :
When you’re looking to invest in a fluid bed dryer system, keep in mind all the features that are important to you and don’t compromise. Consider all that is available in a quality fluid bed processor:
• Heat transfer with minimal energy consumption
• Multi-functional: capable of heating, drying, cooling, coating, and more
• Adaptable to continuous or batch processing
• Vibration to aid in processing
• Manufactured from stainless steel, carbon steel, or nickel alloy
• Customized for your individual needs
• Low maintenance

“THE BOMBAY ENGINEERING WORKS” fluid bed dryers have all the above-listed features and technical engineers can help you plan, install and maintain your equipment for efficient, optimum output.
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Talk to our Knowledgeable Staff :
If you’d like to learn more or you have additional questions, “THE BOMBAY ENGINEERING WORKS” has the answers. Our team is ready to help you design a fluidized bed system that meets all of your requirements. No matter where you’re located, we’ll help you design a custom solution that will meet your specific needs.
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